Alpha GPC is consistently touted as the perhaps best source of choline, and I've snooped around pubmed and followed up articles and gotten a decent impression of why this is. There are a handful of studies that link it more than most anything else (except for maybe CDP-choline) with higher acetylcholine levels.
On the other hand, taking it with piracetam has not yielded a great effect, and I have not figured out why.
The first time I took it with piracetam I got headaches until I stacked it with a gram of choline citrate, which got rid of them for good. And once I'd run out of AGPC, the choline citrate did just fine on its own. In fact the combined effect of choline citrate and piracetam was qualitatively identical and only a little less pronounced than it had been when with AGPC, choline citrate, and piracetam combined, and the degree of THAT effect was nearly identical in both intensity and quality to a combination of DMAE and piracetam. I probably don't need to mention how much cheaper DMAE is to Alpha GPC, reputation or no.
The other choline source that works by a similar mechanism to AGPC is CDP-choline, which is more extensively studied and also linked to slight mood enhancement. I've not found a bulk powder source but it strikes me as a superior supplement.
I'm a 25 year old healthy male, by the way. Your mileage may vary. My advice is this: definitely consider trying a cheaper choline source before settling on AGPC, and don't give into the idea that because AGPC is linked to a few of the most promising studies (primarily for patients of brain disorders) that it *must* to be the best choline source. The results have not spoken thus for my own physiology and purposes, and I have tried both BN's bulk powder and Jarrow's pharm-grade stuff. |
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